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Notch signalling pathway is Just about the most conserved signalling pathways activated in embryonic vasculature advancement 160. In Drosophila, Notch signalling is delicate to environmental sterol amounts. The expression degree of Notch signalling is modulated by dietary cholesterol, causing intestinal cell differentiation from stemness position 1
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Caudatin induced ubiquitin (Ub)-dependent glucocorticoid receptor (GR) degradation and blocked subsequent Indeed-involved protein (YAP) nuclear accumulation and goal gene transcription signals in BCSCs. These effects show the GR/YAP signaling pathway regulates BCSC development Which caudatin can be a possible chemopreventive agent that targets brea
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